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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL129476
Molecular formula	C22H24N2O
IUPAC name	4-(5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl)-1-phenylbutan-1-one
Molecular weight	332.447
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.6
Synonyms	BDBM50132108 4-(5-Methyl-1,3,4,5-tetrahydro-pyrido[4,3-b]indol-2-yl)-1-phenyl-butan-1-one
Inchi Key	PVSIEIHLLNZYRZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24N2O/c1-23-20-11-6-5-10-18(20)19-16-24(15-13-21(19)23)14-7-12-22(25)17-8-3-2-4-9-17/h2-6,8-11H,7,12-16H2,1H3
PubChem CID	44351342
ChEMBL	CHEMBL129476
IUPHAR	N/A
BindingDB	50132108
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
270076	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
270074	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
270075	5-hydroxytryptamine receptor 5A	P30966	Htr5a	Mus musculus (Mouse)	357

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