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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2322875
Molecular formula	C18H19Cl2F3N4O2
IUPAC name	1-[4-(4-chloro-3-methoxyphenyl)piperazin-1-yl]-2-[4-chloro-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]ethanone
Molecular weight	451.271
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.0
Synonyms	BDBM50427065 PTHJVFQTMJMDKU-UHFFFAOYSA-N 1-[4-(4-Chloro-3-methoxy-phenyl)-piperazin-1-yl]-2-(4-chloro-5-methyl-3-trifluoromethyl-pyrazol-1-yl)-ethanone SCHEMBL2866978
Inchi Key	PTHJVFQTMJMDKU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H19Cl2F3N4O2/c1-11-16(20)17(18(21,22)23)24-27(11)10-15(28)26-7-5-25(6-8-26)12-3-4-13(19)14(9-12)29-2/h3-4,9H,5-8,10H2,1-2H3
PubChem CID	21070989
ChEMBL	CHEMBL2322875
IUPHAR	N/A
BindingDB	50427065
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
268365	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
268366	C-C chemokine receptor type 1	P51675	Ccr1	Mus musculus (Mouse)	355

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