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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-366,811
Molecular formula	C43H56N8O6
IUPAC name	N-(2-amino-3-methylpentanoyl)-N-[1-(1H-indol-3-yl)-3-oxopropan-2-yl]-1-[2-(methylamino)-3-[6-(piperazine-1-carbonyl)-6-(2H-pyridine-1-carbonyl)cyclohexa-1,3-dien-1-yl]propanoyl]pyrrolidine-2-carboxamide
Molecular weight	780.971
Hydrogen bond acceptor	9
Hydrogen bond donor	4
XlogP	2.2
Synonyms	NSC_3083084 CAS_3083084 BDBM81893
Inchi Key	PQTORSHXODXZHK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C43H56N8O6/c1-4-29(2)37(44)40(55)51(32(28-52)25-30-27-47-34-15-7-6-14-33(30)34)39(54)36-16-12-22-50(36)38(53)35(45-3)26-31-13-8-9-17-43(31,41(56)48-20-10-5-11-21-48)42(57)49-23-18-46-19-24-49/h5-11,13-15,20,27-29,32,35-37,45-47H,4,12,16-19,21-26,44H2,1-3H3
PubChem CID	54592344
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81893
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
266481	Oxytocin receptor	P70536	Oxtr	Rattus norvegicus (Rat)	388
266482	Oxytocin receptor	P30559	OXTR	Homo sapiens (Human)	389
266483	Oxytocin receptor	P56494	OXTR	Macaca mulatta (Rhesus macaque)	389
266484	Vasopressin V2 receptor	Q00788	Avpr2	Rattus norvegicus (Rat)	371

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