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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	HTFMT
Molecular formula	C19H25F3N4O
IUPAC name	6-[2-(1H-imidazol-5-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]heptanamide
Molecular weight	382.431
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.1
Synonyms	6-[2-(1H-imidazol-5-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]heptanamide GTPL1273 L024081 BRD-A66435872-313-01-8 Histamine trifluoromethyl-toluidide 103827-16-3 CHEMBL67601 6-[2-(3H-imidazol-4-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]heptanamide Heptanamide, 6-((2-(1H-imidazol-4-yl)ethyl)amino)-N-(4-(trifluoromethyl)phenyl)- NCGC00024706-02 CHEBI:91812 histamine-trifluoromethyl-toluidine D09UVB HTMT AC1L3Z71 Histamine trifluoromethyl toluidide histamine-trifluoromethyltoluide [ Show all ]
Inchi Key	PMKJGGBYYNEYPA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27)
PubChem CID	124846
ChEMBL	CHEMBL67601
IUPHAR	1273
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
263356	Histamine H2 receptor	P97292	Hrh2	Mus musculus (Mouse)	397
452122	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
554580	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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