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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL544427
Molecular formula	C21H26ClNO5
IUPAC name	ethyl 2-[2-chloro-4-[2-[[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]phenoxy]acetate
Molecular weight	407.891
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	3.6
Synonyms	BDBM50122649 L019413 (2-Chloro-4-{2-[2-hydroxy-2-(4-hydroxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenoxy)-acetic acid ethyl ester; hydrochloride CHEMBL1193081
Inchi Key	OWJSVNHNFSCPRV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26ClNO5/c1-3-27-20(25)13-28-19-9-4-15(12-18(19)22)10-11-23-14(2)21(26)16-5-7-17(24)8-6-16/h4-9,12,14,21,23-24,26H,3,10-11,13H2,1-2H3
PubChem CID	11611195
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50122649
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
251904	Beta-2 adrenergic receptor	P54833	ADRB2	Canis lupus familiaris (Dog)	415
251905	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
251903	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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