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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	STA2
Molecular formula	C21H34O3S
IUPAC name	(Z)-7-[(1S,2R,5S)-3-[(E,3S)-3-hydroxyoct-1-enyl]-6-thiabicyclo[3.1.1]heptan-2-yl]hept-5-enoic acid
Molecular weight	366.56
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.9
Synonyms	STA 2 89617-02-7 BDBM81948 ONO 11113 5-Heptenoic acid, 7-(3-(3-hydroxy-1-octenyl)-6-thiabicyclo(3.1.1)hept-2-yl)-, (1S-(1alpha,2beta(Z),3alpha(1E,3R*),5alpha))- STA-2 9,11-Epithio-11,12-methano-TXA2 CAS_89617-02-7 111200-21-6 ONO-11113 9,11-Epithio-11,12-methanothromboxane A2 ONO 11,113 5-Heptenoic acid, 7-((1S,2R,4R,5S)-3-((1E,3S)-3-hydroxy-1-octenyl)-6-thiabicyclo(3.1.1)hept-2-yl)-, (5Z)- [ Show all ]
Inchi Key	OVGWMUWIRHGGJP-YUOWJYRGSA-N
Inchi ID	InChI=1S/C21H34O3S/c1-2-3-6-9-17(22)13-12-16-14-18-15-20(25-18)19(16)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16?,17-,18-,19+,20-/m0/s1
PubChem CID	6439867
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81948
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
251174	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
556440	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
251173	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
251172	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
461382	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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