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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-FA554TW3UP
Molecular formula	C24H28N2O3
IUPAC name	N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide
Molecular weight	392.499
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.2
Synonyms	GTPL9004 NCGC00346641-07 BDBM50252954 CHEMBL494480 N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4''-piperidine]-4-yl)benzamide SCHEMBL467481 FA554TW3UP N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidin]-4-yl)benzamide KB-74520 PF-04856880 Benzamide, N,N-diethyl-4-(5-hydroxyspiro(2H-1-benzopyran-2,4'-piperidin)-4-yl)- compound 20 [PMID: 18788723] N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl) benzamide FT-0760130 NCGC00346641-01 ADL 5859 N,N-Diethyl-4-(5-hydroxyspiro[2H-1-benzopyran-2,4'-piperidin]-4-yl)benzamide SB19530 DB-076207 N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide ZINC40424141 850305-06-5 [ Show all ]
Inchi Key	OPIKUXLJQFYMSC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H28N2O3/c1-3-26(4-2)23(28)18-10-8-17(9-11-18)19-16-24(12-14-25-15-13-24)29-21-7-5-6-20(27)22(19)21/h5-11,16,25,27H,3-4,12-15H2,1-2H3
PubChem CID	11417954
ChEMBL	CHEMBL494480
IUPHAR	9004
BindingDB	50252954
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
247017	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
247016	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
528616	Mas-related G-protein coupled receptor member X2	Q96LB1	MRGPRX2	Homo sapiens (Human)	330
247015	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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