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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL185251
Molecular formula	C28H25FN2O5
IUPAC name	2-[1-[4-[[(2S)-7-fluoro-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]-2-methylindol-4-yl]acetic acid
Molecular weight	488.515
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.1
Synonyms	{1-[4-(7-Fluoro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazin-2-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid BDBM50152512 SCHEMBL991800
Inchi Key	OOSKJUCSXNQQLG-QFIPXVFZSA-N
Inchi ID	InChI=1S/C28H25FN2O5/c1-17-12-23-19(13-27(32)33)4-3-5-24(23)31(17)28(34)18-6-9-21(10-7-18)35-16-22-15-30(2)25-11-8-20(29)14-26(25)36-22/h3-12,14,22H,13,15-16H2,1-2H3,(H,32,33)/t22-/m0/s1
PubChem CID	10206535
ChEMBL	CHEMBL185251
IUPHAR	N/A
BindingDB	50152512
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
246587	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
246590	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357
246588	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
246585	Prostaglandin E2 receptor EP2 subtype	Q62053	Ptger2	Mus musculus (Mouse)	362
246586	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
246589	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513

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