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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL417137
Molecular formula	C20H24Cl2N2O4
IUPAC name	2-[2,6-dichloro-4-[2-[[(1R,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]amino]ethyl]-N-methylanilino]acetic acid
Molecular weight	427.322
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	1.4
Synonyms	[[4-[2-[[(1S,2R)-2-(4-Hydroxyphenyl)-2-hydroxy-1-methylethyl]amino]ethyl]-2,6-dichlorophenyl](methyl)amino]acetic acid BDBM50409474 SCHEMBL8072865
Inchi Key	OJEJPISOZCCDJR-YUNKPMOVSA-N
Inchi ID	InChI=1S/C20H24Cl2N2O4/c1-12(20(28)14-3-5-15(25)6-4-14)23-8-7-13-9-16(21)19(17(22)10-13)24(2)11-18(26)27/h3-6,9-10,12,20,23,25,28H,7-8,11H2,1-2H3,(H,26,27)/t12-,20-/m0/s1
PubChem CID	10741134
ChEMBL	CHEMBL417137
IUPHAR	N/A
BindingDB	50409474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
242682	Beta-1 adrenergic receptor	P18090	Adrb1	Rattus norvegicus (Rat)	466
242683	Beta-2 adrenergic receptor	P10608	Adrb2	Rattus norvegicus (Rat)	418
242681	Beta-3 adrenergic receptor	P26255	Adrb3	Rattus norvegicus (Rat)	400

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