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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17418793
Molecular formula	C33H33FN2O4
IUPAC name	(3S)-3-cyclopropyl-3-[3-[[5-(2-fluoro-5-methoxyphenyl)-6-(4-propan-2-ylphenyl)pyrazin-2-yl]methoxy]phenyl]propanoic acid
Molecular weight	540.635
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	6.5
Synonyms	BDBM168160 US9688642, 25 (3S)-3-Cyclopropyl-3-(3-((5-(2-fluoro-5-methoxyphenyl)-6-(4-isopropylphenyl)pyrazin-2-yl)methoxy)phenyl)propanoic acid NLCAAJNMYUAZQJ-NDEPHWFRSA-N
Inchi Key	NLCAAJNMYUAZQJ-NDEPHWFRSA-N
Inchi ID	InChI=1S/C33H33FN2O4/c1-20(2)21-7-11-23(12-8-21)32-33(29-16-26(39-3)13-14-30(29)34)35-18-25(36-32)19-40-27-6-4-5-24(15-27)28(17-31(37)38)22-9-10-22/h4-8,11-16,18,20,22,28H,9-10,17,19H2,1-3H3,(H,37,38)/t28-/m0/s1
PubChem CID	118645571
ChEMBL	N/A
IUPHAR	N/A
BindingDB	168160
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
564396	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300
564397	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300

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