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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	VUF10460
Molecular formula	C15H19N5
IUPAC name	4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine
Molecular weight	269.352
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.8
Synonyms	BCP28979 VUF 10460 4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine CHEMBL492884 AK688823 MolPort-008-426-086 1028327-66-3 BDBM26390 4-(4-methylpiperazin-1-yl)-6-phenylpyrimidin-2-amine CS-6422 AKOS022268844 SCHEMBL2167865 ZINC36139575 6-aryl-2-aminopyrimidine, 3 HY-101420 [ Show all ]
Inchi Key	NIJGWJIOMPHDBP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H19N5/c1-19-7-9-20(10-8-19)14-11-13(17-15(16)18-14)12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3,(H2,16,17,18)
PubChem CID	25129523
ChEMBL	CHEMBL492884
IUPHAR	N/A
BindingDB	26390
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
224076	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
224077	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391

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