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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL43297
Molecular formula	C26H29FN4O2
IUPAC name	4-fluoro-N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-3-methyl-N-pyridin-2-ylbenzamide
Molecular weight	448.542
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.3
Synonyms	BDBM50076429 N-(2-Pyridyl)-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-3-methyl-4-fluorobenzamide 4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-3-methyl-N-pyridin-2-yl-benzamide
Inchi Key	MWCWNEWLVWIYOH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H29FN4O2/c1-20-19-21(10-11-22(20)27)26(32)31(25-9-5-6-12-28-25)18-15-29-13-16-30(17-14-29)23-7-3-4-8-24(23)33-2/h3-12,19H,13-18H2,1-2H3
PubChem CID	10623356
ChEMBL	CHEMBL43297
IUPHAR	N/A
BindingDB	50076429
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
215728	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
215729	5-hydroxytryptamine receptor 1D	Q61224	Htr1d	Mus musculus (Mouse)	374
215730	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466

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