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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3926121
Molecular formula	C12H20N6OS
IUPAC name	3-N-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1H-1,2,4-triazole-3,5-diamine
Molecular weight	296.393
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	1.1
Synonyms	MPCHFTDBRPKJLW-UHFFFAOYSA-N N5 -[2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-1H-1,2,4-triazole-3,5-diamine SCHEMBL11356692 BDBM50199151
Inchi Key	MPCHFTDBRPKJLW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H20N6OS/c1-18(2)7-9-3-4-10(19-9)8-20-6-5-14-12-15-11(13)16-17-12/h3-4H,5-8H2,1-2H3,(H4,13,14,15,16,17)
PubChem CID	70570522
ChEMBL	CHEMBL3926121
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
541508	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
541507	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
541509	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
541506	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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