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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL503735
Molecular formula	C16H9ClF3NO2
IUPAC name	7-chloro-1-[[4-(trifluoromethyl)phenyl]methyl]indole-2,3-dione
Molecular weight	339.698
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.9
Synonyms	VU0238441-1 BDBM50258723 KB-81466 ZINC40828817 7-chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione VU0238441 85511-68-8 [ Show all ]
Inchi Key	MIAQTWNDRFRVOQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H9ClF3NO2/c17-12-3-1-2-11-13(12)21(15(23)14(11)22)8-9-4-6-10(7-5-9)16(18,19)20/h1-7H,8H2
PubChem CID	44158142
ChEMBL	CHEMBL503735
IUPHAR	N/A
BindingDB	50258723
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
205998	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
205994	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
205996	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
205997	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
205995	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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