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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	TPMPA
Molecular formula	C6H12NO2P
IUPAC name	methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
Molecular weight	161.141
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	-3.5
Synonyms	(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid Biomol-NT_000236 MolPort-003-959-683 CHEMBL397209 Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)- UNII-TR7I0800L2 B6562 methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid SR-01000075623 (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinsaure BPBio1_000464 NCGC00163284-01 Tpmpa [MI] AC1L1KJ2 CTK7B4413 RT-016053 ZINC25720700 BDBM50211642 Methyl(1,2,3,6-tetrahydropyridinium-4-yl)phosphinate SR-01000075623-1 182485-36-5 P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid TR7I0800L2 AKOS006344745 J-011675 SCHEMBL678239 [ Show all ]
Inchi Key	MFUKVPOVVKKLRQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)
PubChem CID	5521
ChEMBL	CHEMBL397209
IUPHAR	N/A
BindingDB	50211642
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
204393	Gamma-aminobutyric acid type B receptor subunit 1	Q9UBS5	GABBR1	Homo sapiens (Human)	961
204392	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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