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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355961
Molecular formula	C32H35F2N3O2S
IUPAC name	ethyl 6-[2-ethyl-6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]indol-1-yl]pyridine-2-carboxylate
Molecular weight	563.708
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	7.7
Synonyms	BDBM50041199 SCHEMBL1098360
Inchi Key	MFNWFHKBFKEKAN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H35F2N3O2S/c1-3-28-31(22-15-18-36(19-16-22)17-6-20-40-25-12-9-23(33)10-13-25)26-14-11-24(34)21-29(26)37(28)30-8-5-7-27(35-30)32(38)39-4-2/h5,7-14,21-22H,3-4,6,15-20H2,1-2H3
PubChem CID	25024850
ChEMBL	CHEMBL3355961
IUPHAR	N/A
BindingDB	50041199
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
449724	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
449725	C-C chemokine receptor type 3	O54814	Ccr3	Rattus norvegicus (Rat)	359
449723	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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