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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL197375
Molecular formula	C24H27ClFN3O2
IUPAC name	N-[5-chloro-2-[(E)-3-[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide
Molecular weight	443.947
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.9
Synonyms	SCHEMBL3167876 BDBM50174708 N-(2-(3-((2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)acetamide
Inchi Key	MDORNLMADCVHFZ-CZPJPAAGSA-N
Inchi ID	InChI=1S/C24H27ClFN3O2/c1-16-14-29(17(2)13-28(16)15-19-4-9-22(26)10-5-19)24(31)11-7-20-6-8-21(25)12-23(20)27-18(3)30/h4-12,16-17H,13-15H2,1-3H3,(H,27,30)/b11-7+/t16-,17+/m0/s1
PubChem CID	10456104
ChEMBL	CHEMBL197375
IUPHAR	N/A
BindingDB	50174708
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
202878	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
202879	C-C chemokine receptor type 1	P51675	Ccr1	Mus musculus (Mouse)	355

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