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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3355957
Molecular formula	C28H34F2N2O2S
IUPAC name	ethyl 2-[2-ethyl-6-fluoro-3-[1-[3-(4-fluorophenyl)sulfanylpropyl]piperidin-4-yl]indol-1-yl]acetate
Molecular weight	500.649
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	6.6
Synonyms	BDBM50041202 SCHEMBL1097577
Inchi Key	MAFSPAYMPQWVRE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H34F2N2O2S/c1-3-25-28(24-11-8-22(30)18-26(24)32(25)19-27(33)34-4-2)20-12-15-31(16-13-20)14-5-17-35-23-9-6-21(29)7-10-23/h6-11,18,20H,3-5,12-17,19H2,1-2H3
PubChem CID	24937092
ChEMBL	CHEMBL3355957
IUPHAR	N/A
BindingDB	50041202
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
449587	C-C chemokine receptor type 3	P51677	CCR3	Homo sapiens (Human)	355
449588	Probable C-C chemokine receptor type 3	P51678	Ccr3	Mus musculus (Mouse)	359

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