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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775169
Molecular formula	C22H27N5O5S
IUPAC name	tert-butyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	473.548
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.8
Synonyms	LZCNLEZPKDPKSO-UHFFFAOYSA-N tert-butyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl]oxypiperidine-1-carboxylate 142831-EP2292620A2 D08HOK SCHEMBL389425 142831-EP2287165A2 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid tert-butyl ester GTPL5737 BDBM50343447 tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate 142831-EP2287166A2 compound 3a [PMID: 21444206] [ Show all ]
Inchi Key	LZCNLEZPKDPKSO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27N5O5S/c1-22(2,3)32-21(28)26-11-9-16(10-12-26)31-20-18-13-25-27(19(18)23-14-24-20)15-5-7-17(8-6-15)33(4,29)30/h5-8,13-14,16H,9-12H2,1-4H3
PubChem CID	11282871
ChEMBL	CHEMBL1775169
IUPHAR	5737
BindingDB	50343447
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
199905	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335
199906	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468

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