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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS002162744
Molecular formula	C21H24N4O2
IUPAC name	6-cyclopropyl-N-[(4-methoxyphenyl)methyl]-1-propan-2-ylpyrazolo[3,4-b]pyridine-4-carboxamide
Molecular weight	364.449
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.9
Synonyms	HMS3040D24 MolPort-004-157-990 6-cyclopropyl-N-[(4-methoxyphenyl)methyl]-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxamide ZINC8226309 MCULE-1054565951 SMR001245144 878443-23-3 CHEMBL1316330 Z52022640 AKOS034427855 [ Show all ]
Inchi Key	KKSWMHOVTCOBIY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24N4O2/c1-13(2)25-20-18(12-23-25)17(10-19(24-20)15-6-7-15)21(26)22-11-14-4-8-16(27-3)9-5-14/h4-5,8-10,12-13,15H,6-7,11H2,1-3H3,(H,22,26)
PubChem CID	9357701
ChEMBL	CHEMBL1316330
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
171481	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
171482	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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