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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL209459
Molecular formula	C25H34N4O3S
IUPAC name	N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]cyclopropanecarboxamide
Molecular weight	470.632
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.2
Synonyms	BDBM50187378 cyclopropanecarboxylic acid (3-{4-[4-(toluene-4-sulfonylamino)-butyl]-piperazin-1-yl}-phenyl)-amide SCHEMBL13532843
Inchi Key	JONFWGAWADRHQO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H34N4O3S/c1-20-7-11-24(12-8-20)33(31,32)26-13-2-3-14-28-15-17-29(18-16-28)23-6-4-5-22(19-23)27-25(30)21-9-10-21/h4-8,11-12,19,21,26H,2-3,9-10,13-18H2,1H3,(H,27,30)
PubChem CID	10254142
ChEMBL	CHEMBL209459
IUPHAR	N/A
BindingDB	50187378
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
156055	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
156056	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450

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