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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000775763
Molecular formula	C21H16F2N2O5S
IUPAC name	N-[4-(difluoromethylsulfanyl)phenyl]-5-(2-hydroxy-5-methoxybenzoyl)-2-iminopyran-3-carboxamide
Molecular weight	446.425
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	4.6
Synonyms	MolPort-004-262-291 Z44426736 BDBM57969 CHEMBL1453924 N-[4-(difluoromethylthio)phenyl]-5-[(2-hydroxy-5-methoxyphenyl)-oxomethyl]-2-imino-3-pyrancarboxamide MCULE-6963572888 SR-01000043980 AC1M6YJZ N-[4-(difluoromethylsulfanyl)phenyl]-5-(2-hydroxy-5-methoxybenzoyl)-2-iminopyran-3-carboxamide ZINC9579682 CHEBI:112676 cid_2432552 N-{4-[(difluoromethyl)sulfanyl]phenyl}-5-(2-hydroxy-5-methoxybenzoyl)-2-imino-2H-pyran-3-carboxamide 2-azanylidene-N-[4-[bis(fluoranyl)methylsulfanyl]phenyl]-5-(5-methoxy-2-oxidanyl-phenyl)carbonyl-pyran-3-carboxamide SR-01000043980-1 AKOS034348161 N-[4-(difluoromethylthio)phenyl]-5-(2-hydroxy-5-methoxy-benzoyl)-2-imino-pyran-3-carboxamide HMS2706P14 SMR000369329 565179-41-1 [ Show all ]
Inchi Key	JOLCWSYBUSOJKF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H16F2N2O5S/c1-29-13-4-7-17(26)15(9-13)18(27)11-8-16(19(24)30-10-11)20(28)25-12-2-5-14(6-3-12)31-21(22)23/h2-10,21,24,26H,1H3,(H,25,28)
PubChem CID	2432552
ChEMBL	CHEMBL1453924
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
155978	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
155977	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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