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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-methylpropyl 6-(6-bromo(2H-benzo[d]1,3-dioxolan-5-yl))-3,4-dimethyl-2-oxo-1, 3,6-trihydropyrimidine-5-carboxylate
Molecular formula	C18H21BrN2O5
IUPAC name	2-methylpropyl 6-(6-bromo-1,3-benzodioxol-5-yl)-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate
Molecular weight	425.279
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.0
Synonyms	2-methylpropyl 6-(6-bromo-1,3-benzodioxol-5-yl)-3,4-dimethyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate ChemDiv1_001359 MolPort-000-904-260 STK363311 AKOS000654997 HMS590N17 Oprea1_576432 2-methylpropyl 4-(6-bromo-1,3-benzodioxol-5-yl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate MLS000108134 SR-01000411178-1 AC1MF2JK HMS2168F24 NCGC00079570-02 AKOS022064410 isobutyl 4-(6-bromo-1,3-benzodioxol-5-yl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate SMR000104096 CHEMBL1337167 MLS002539987 ST014862 AG-690/11821792 HMS3312B10 Oprea1_286366 BAS 00714452 MCULE-9869833411 SR-01000411178 [ Show all ]
Inchi Key	JDZXOFUYCFMXGR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H21BrN2O5/c1-9(2)7-24-17(22)15-10(3)21(4)18(23)20-16(15)11-5-13-14(6-12(11)19)26-8-25-13/h5-6,9,16H,7-8H2,1-4H3,(H,20,23)
PubChem CID	2864940
ChEMBL	CHEMBL1337167
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
148650	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
148651	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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