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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL46527
Molecular formula	C8H11NO4
IUPAC name	(1R,2S,4R,5R)-2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic acid
Molecular weight	185.179
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-3.2
Synonyms	(1R,2S,4R,5R)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid BDBM50064246 (1R,4R)-2beta-Aminobicyclo[2.1.1]hexane-2,5beta-dicarboxylic acid
Inchi Key	JCGJEPFYMOHIDP-DJSMDIAISA-N
Inchi ID	InChI=1S/C8H11NO4/c9-8(7(12)13)2-3-1-4(8)5(3)6(10)11/h3-5H,1-2,9H2,(H,10,11)(H,12,13)/t3-,4-,5-,8+/m1/s1
PubChem CID	10775369
ChEMBL	CHEMBL46527
IUPHAR	N/A
BindingDB	50064246
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
147374	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
147375	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
147372	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
147371	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
147373	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877

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