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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AG 045572
Molecular formula	C30H37NO5
IUPAC name	5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]-N-(2,4,6-trimethoxyphenyl)furan-2-carboxamide
Molecular weight	491.628
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	7.5
Synonyms	B7163 GTPL1179 ZINC1910570 5-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl]-N-(2,4,6-trimethoxyphenyl)furan-2-carboxamide CHEMBL494803 MolPort-023-276-560 DTXSID50433309 RT-011204 263847-55-8 BDBM50261184 J-016407 5-[5,6,7,8-TETRAHYDRO-3,5,5,8,8-PENTAMETHYL-2-NAPHTHALENYL-METHYL]-N-(2,4,6-TRIMETHOXYPHENYL)-2-FURANCARBOXAMIDE CTK8E8783 N-(2,4,6-Trimethoxyphenyl)-5-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-yl)methyl]furan-2-carboxamide AKOS024457264 Furan-1 SCHEMBL208907 5-((3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)-N-(2,4,6-trimethoxyphenyl)furan-2-carboxamide L021269 D00HNG NCGC00378704-01 [ Show all ]
Inchi Key	IPEMCIBPDYCJLO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H37NO5/c1-18-13-22-23(30(4,5)12-11-29(22,2)3)15-19(18)14-20-9-10-24(36-20)28(32)31-27-25(34-7)16-21(33-6)17-26(27)35-8/h9-10,13,15-17H,11-12,14H2,1-8H3,(H,31,32)
PubChem CID	9957278
ChEMBL	CHEMBL494803
IUPHAR	1179
BindingDB	50261184
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
138530	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327
138531	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328
138532	Gonadotropin-releasing hormone receptor	Q01776	Gnrhr	Mus musculus (Mouse)	327

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