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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001138759
Molecular formula	C28H30N4O6
IUPAC name	[2-[(6-amino-1-benzyl-2,4-dioxopyrimidin-5-yl)-(2-methylpropyl)amino]-2-oxoethyl] 2-(6-methyl-1-benzofuran-3-yl)acetate
Molecular weight	518.57
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.4
Synonyms	MCULE-8046531926 SMR000710288 CHEMBL1327994 ZINC24773098 AKOS008019056 HMS3022H08 MolPort-005-737-011 [ Show all ]
Inchi Key	IJDXDKGEZKHTMU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H30N4O6/c1-17(2)13-31(25-26(29)32(28(36)30-27(25)35)14-19-7-5-4-6-8-19)23(33)16-38-24(34)12-20-15-37-22-11-18(3)9-10-21(20)22/h4-11,15,17H,12-14,16,29H2,1-3H3,(H,30,35,36)
PubChem CID	24980222
ChEMBL	CHEMBL1327994
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
134460	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
134459	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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