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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000218862
Molecular formula	C22H16ClNO4
IUPAC name	(2-oxo-3-quinolin-2-ylchromen-7-yl) 4-chlorobutanoate
Molecular weight	393.823
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.5
Synonyms	CHEMBL1480809 STK609849 4-Chloro-butyric acid 2-oxo-3-quinolin-2-yl-2H-chromen-7-yl ester 796880-44-9 MCULE-9382273157 BDBM90156 2-oxo-3-(2-quinolyl)chromen-7-yl 4-chlorobutanoate cid_1835281 ZINC17354100 4-chlorobutanoic acid [2-oxo-3-(2-quinolinyl)-1-benzopyran-7-yl] ester AC1LXR9L MLS000591251 (2-oxidanylidene-3-quinolin-2-yl-chromen-7-yl) 4-chloranylbutanoate ST51027699 2-oxo-3-(quinolin-2-yl)-2H-chromen-7-yl 4-chlorobutanoate HMS2589L05 4-chlorobutyric acid [2-keto-3-(2-quinolyl)chromen-7-yl] ester AKOS005544762 MolPort-000-832-443 (2-oxo-3-quinolin-2-ylchromen-7-yl) 4-chlorobutanoate [ Show all ]
Inchi Key	IJAVBJVEKJZMOK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H16ClNO4/c23-11-3-6-21(25)27-16-9-7-15-12-17(22(26)28-20(15)13-16)19-10-8-14-4-1-2-5-18(14)24-19/h1-2,4-5,7-10,12-13H,3,6,11H2
PubChem CID	1835281
ChEMBL	CHEMBL1480809
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
134394	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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