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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL299213
Molecular formula	C16H22N6
IUPAC name	2-[5-[(2-ethyltetrazol-5-yl)methyl]-1H-indol-3-yl]-N,N-dimethylethanamine
Molecular weight	298.394
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.8
Synonyms	N,N-Dimethyl-5-[(2-ethyl-2H-tetrazol-5-yl)methyl]-1H-indole-3-(ethanamine) SCHEMBL8784514 BDBM50407354
Inchi Key	IIYLGSKFTYDEID-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H22N6/c1-4-22-19-16(18-20-22)10-12-5-6-15-14(9-12)13(11-17-15)7-8-21(2)3/h5-6,9,11,17H,4,7-8,10H2,1-3H3
PubChem CID	10063283
ChEMBL	CHEMBL299213
IUPHAR	N/A
BindingDB	50407354
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
134339	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
134336	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
134338	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
134337	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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