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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000777053
Molecular formula	C21H12N2O4S
IUPAC name	3-[5-[(E)-(1-oxo-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid
Molecular weight	388.397
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.4
Synonyms	cid_1976940 STK084967 3-{5-[(E)-(3-oxo[1,3]thiazolo[3,2-a]benzimidazol-2(3H)-ylidene)methyl]furan-2-yl}benzoic acid AKOS001677436 3-[5-[(E)-(1-ketothiazolo[3,2-a]benzimidazol-2-ylidene)methyl]-2-furyl]benzoic acid SR-01000495276 3-[5-[(E)-(1-oxo-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid 3-{5-[3-Oxo-benzo[4,5]imidazo[2,1-b]thiazol-(2E)-ylidenemethyl]-furan-2-yl}-benzoic acid HMS1482F03 ZINC13798980 BDBM114259 MolPort-002-563-456 3-[5-[(E)-(1-oxidanylidene-[1,3]thiazolo[3,2-a]benzimidazol-2-ylidene)methyl]furan-2-yl]benzoic acid CHEMBL1991573 SR-01000495276-1 3-{5-[(E)-(3-oxo[1,3]thiazolo[3,2-a]benzimidazol-2(3H)-ylidene)methyl]-2-furyl}benzoic acid AC1LZL7P IDI1_021191 BRD-K14109741-001-01-0 SMR000413437 3-[5-[(E)-(1-oxo-2-thiazolo[3,2-a]benzimidazolylidene)methyl]-2-furanyl]benzoic acid [ Show all ]
Inchi Key	IHXPBZYKWITPFM-WOJGMQOQSA-N
Inchi ID	InChI=1S/C21H12N2O4S/c24-19-18(28-21-22-15-6-1-2-7-16(15)23(19)21)11-14-8-9-17(27-14)12-4-3-5-13(10-12)20(25)26/h1-11H,(H,25,26)/b18-11+
PubChem CID	1976940
ChEMBL	CHEMBL1991573
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
133646	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
133647	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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