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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL59830
Molecular formula	C8H14N2O4
IUPAC name	(2R,4R)-4-amino-1-ethylpyrrolidine-2,4-dicarboxylic acid
Molecular weight	202.21
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-5.7
Synonyms	(2R,4R)-4-Amino-1-ethyl-pyrrolidine-2,4-dicarboxylic acid 213619-99-9 ZINC26157741 BDBM50071156 (2R,4R)-4-amino-1-ethylpyrrolidine-2,4-dicarboxylic acid CTK1A0057 2,4-Pyrrolidinedicarboxylicacid, 4-amino-1-ethyl-, (2R,4R)- DTXSID80658240 AKOS027402607 [ Show all ]
Inchi Key	IDVBYGZWDIPMSF-SVGQVSJJSA-N
Inchi ID	InChI=1S/C8H14N2O4/c1-2-10-4-8(9,7(13)14)3-5(10)6(11)12/h5H,2-4,9H2,1H3,(H,11,12)(H,13,14)/t5-,8-/m1/s1
PubChem CID	44302837
ChEMBL	CHEMBL59830
IUPHAR	N/A
BindingDB	50071156
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
130836	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
130838	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
130837	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
130839	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
130835	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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