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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	glucagon receptor antagonists-4
Molecular formula	C26H28F3N3O4
IUPAC name	3-[[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)pyrazol-1-yl]phenoxy]butyl]benzoyl]amino]propanoic acid
Molecular weight	503.522
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.0
Synonyms	PF-06291874, >=98% (HPLC) EX-A1994 UNII-CGY4I8F278 beta-Alanine, N-(4-((1S)-1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzoyl)- IBDYYOQKQCCSDP-QFIPXVFZSA-N (S)-3-(4-(1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenoxy)butyl)benzamido)propanoic acid CHEMBL2381848 PF06291874; Glucagon receptor antagonists-4 AKOS030526091 ZINC96269688 CGY4I8F278 PF-06291874 1393124-08-7 CS-5665 SCHEMBL11901097 BDBM50433577 HY-19947 [ Show all ]
Inchi Key	IBDYYOQKQCCSDP-QFIPXVFZSA-N
Inchi ID	InChI=1S/C26H28F3N3O4/c1-4-5-22(18-6-8-19(9-7-18)25(35)30-11-10-23(33)34)36-21-12-16(2)24(17(3)13-21)32-15-20(14-31-32)26(27,28)29/h6-9,12-15,22H,4-5,10-11H2,1-3H3,(H,30,35)(H,33,34)/t22-/m0/s1
PubChem CID	60151939
ChEMBL	CHEMBL2381848
IUPHAR	N/A
BindingDB	50433577
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
129010	Glucagon receptor	P47871	GCGR	Homo sapiens (Human)	477
129011	Glucagon receptor	P30082	Gcgr	Rattus norvegicus (Rat)	485
129012	Glucagon receptor	Q61606	Gcgr	Mus musculus (Mouse)	485
129013	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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