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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL379364
Molecular formula	C25H36N4O3S
IUPAC name	2-methyl-N-[3-[4-[4-[(4-methylphenyl)sulfonylamino]butyl]piperazin-1-yl]phenyl]propanamide
Molecular weight	472.648
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.8
Synonyms	SCHEMBL3867617 BDBM50187391 N-(3-{4-[4-(toluene-4-sulfonylamino)-butyl]-piperazin-1-yl}-phenyl)-isobutyramide
Inchi Key	IACGINNKBMVURM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H36N4O3S/c1-20(2)25(30)27-22-7-6-8-23(19-22)29-17-15-28(16-18-29)14-5-4-13-26-33(31,32)24-11-9-21(3)10-12-24/h6-12,19-20,26H,4-5,13-18H2,1-3H3,(H,27,30)
PubChem CID	10367560
ChEMBL	CHEMBL379364
IUPHAR	N/A
BindingDB	50187391
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
128268	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
128267	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450

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