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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001122797
Molecular formula	C23H26ClN3O4S
IUPAC name	1-[(1-acetyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide
Molecular weight	475.988
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	1-[(1-acetyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl]-N-(3-chlorophenyl)-3-piperidinecarboxamide cid_20901955 AKOS001932225 1-(1-acetyl-2-methyl-indolin-5-yl)sulfonyl-N-(3-chlorophenyl)nipecotamide N-(3-chlorophenyl)-1-[(1-ethanoyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl]piperidine-3-carboxamide 1-[(1-acetyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide HMS2928F05 AKOS021595074 MLS003880946 1-[(1-acetyl-2-methyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-N-(3-chlorophenyl)piperidine-3-carboxamide CHEMBL1421589 SMR000628395 MCULE-4951017914 BDBM80041 MolPort-007-742-787 [ Show all ]
Inchi Key	HUAWISZIUATZGS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26ClN3O4S/c1-15-11-18-12-21(8-9-22(18)27(15)16(2)28)32(30,31)26-10-4-5-17(14-26)23(29)25-20-7-3-6-19(24)13-20/h3,6-9,12-13,15,17H,4-5,10-11,14H2,1-2H3,(H,25,29)
PubChem CID	20901955
ChEMBL	CHEMBL1421589
IUPHAR	N/A
BindingDB	80041
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
124115	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
124114	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
478223	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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