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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	o-Desmethyl metoclopramide
Molecular formula	C13H20ClN3O2
IUPAC name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide
Molecular weight	285.772
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.8
Synonyms	SCHEMBL8746079 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenz amide CHEMBL43695 38339-95-6 AKOS030577911 HPSMMIJTHMWCGC-UHFFFAOYSA-N 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-hydroxy-benzamide Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxy- UNII-P5DX3Q3OG4 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide CTK1B4964 4-amino-5- chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide BDBM50023811 Metoclopramide specified impurity F [EP] 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxy benzamide P5DX3Q3OG4 ZINC4213841 2-Hydroxy-4-amino-5-chloro-N,N-diethylaminoethylbenzamide DTXSID40191704 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxybenzamide Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxy- N-[2-(Diethylamino)ethyl]-4-amino-5-chloro-2-hydroxybenzamide [ Show all ]
Inchi Key	HPSMMIJTHMWCGC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H20ClN3O2/c1-3-17(4-2)6-5-16-13(19)9-7-10(14)11(15)8-12(9)18/h7-8,18H,3-6,15H2,1-2H3,(H,16,19)
PubChem CID	9817332
ChEMBL	CHEMBL43695
IUPHAR	N/A
BindingDB	50023811
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
120948	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
120949	D(2) dopamine receptor	Q9GJU1	DRD2	Canis lupus familiaris (Dog)	443

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