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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(2) dopamine receptor
Species	Canis lupus familiaris (Dog)
Gene	DRD2
Synonym	Dopamine D2 receptor
Disease	N/A for non-human GPCRs
Length	443
Amino acid sequence	MDPLNLSWYDDDLESQNWSRPFNGSEGKPGKPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTERSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTADSPAKPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCECNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProt	Q9GJU1
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2703
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	o-Desmethyl metoclopramide
Molecular formula	C13H20ClN3O2
IUPAC name	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide
Molecular weight	285.772
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	2.8
Synonyms	4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-hydroxy-benzamide Benzamide, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxy- 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide CTK1B4964 UNII-P5DX3Q3OG4 4-amino-5- chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide BDBM50023811 Metoclopramide specified impurity F [EP] 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxy benzamide P5DX3Q3OG4 2-Hydroxy-4-amino-5-chloro-N,N-diethylaminoethylbenzamide DTXSID40191704 ZINC4213841 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxybenzamide Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-hydroxy- N-[2-(Diethylamino)ethyl]-4-amino-5-chloro-2-hydroxybenzamide 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenz amide CHEMBL43695 SCHEMBL8746079 38339-95-6 AKOS030577911 HPSMMIJTHMWCGC-UHFFFAOYSA-N [ Show all ]
Inchi Key	HPSMMIJTHMWCGC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H20ClN3O2/c1-3-17(4-2)6-5-16-13(19)9-7-10(14)11(15)8-12(9)18/h7-8,18H,3-6,15H2,1-2H3,(H,16,19)
PubChem CID	9817332
ChEMBL	CHEMBL43695
IUPHAR	N/A
BindingDB	50023811
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
ED50	<1.0 mg.kg-1	PMID3397992	ChEMBL

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