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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000172341
Molecular formula	C19H13F3N2O4S
IUPAC name	11-(2,4-dimethoxyphenyl)-6-hydroxy-13-(trifluoromethyl)-8-thia-3,10-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5,10,12-pentaen-4-one
Molecular weight	422.378
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	3.5
Synonyms	7-(2,4-dimethoxyphenyl)-2-hydroxy-9-(trifluoromethyl)hydropyridino[2',3'-4,5]t hiopheno[2,3-b]pyridin-4-one AKOS000666138 HMS2557G22 ZINC18181671 625376-72-9 BDBM50980 MolPort-000-766-779 7-(2,4-dimethoxyphenyl)-4-hydroxy-9-(trifluoromethyl)thieno[2,3-b:4,5-b']dipyridin-2(1H)-one CHEMBL1479883 ST039542 AKOS005710685 MCULE-7013940261 7-(2,4-Dimethoxy-phenyl)-2-hydroxy-9-trifluoromethyl-1H-thieno[2,3-b;4,5-b']dipyridin-4-one C19H13F3N2O4S MolPort-002-007-264 AC1LLLN3 cid_1086490 STL057753 BAS 06901306 MLS000548645 [ Show all ]
Inchi Key	HPEICIGLBWLNLO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H13F3N2O4S/c1-27-8-3-4-9(13(5-8)28-2)11-6-10(19(20,21)22)15-16-17(29-18(15)23-11)12(25)7-14(26)24-16/h3-7H,1-2H3,(H2,24,25,26)
PubChem CID	54684582
ChEMBL	CHEMBL1479883
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
120606	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
120605	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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