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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001199446
Molecular formula	C17H13FO5S
IUPAC name	3-(4-fluoro-3-methylphenyl)sulfonyl-7-hydroxy-8-methylchromen-2-one
Molecular weight	348.344
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.4
Synonyms	MLS-0323357.0001 AKOS001812404 CHEMBL1532646 ZINC6736739 3-(4-fluoranyl-3-methyl-phenyl)sulfonyl-8-methyl-7-oxidanyl-chromen-2-one HMS2850P07 3-(4-fluoro-3-methylphenyl)sulfonyl-7-hydroxy-8-methylchromen-2-one BDBM90881 cid_20864499 3-(4-fluoro-3-methyl-phenyl)sulfonyl-7-hydroxy-8-methyl-coumarin MCULE-8650898615 3-[(4-fluoro-3-methylphenyl)sulfonyl]-7-hydroxy-8-methyl-2H-chromen-2-one SMR000562864 HMS1626P20 3-(4-fluoro-3-methylphenyl)sulfonyl-7-hydroxy-8-methyl-1-benzopyran-2-one [ Show all ]
Inchi Key	HLGILKFCTLIAPA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H13FO5S/c1-9-7-12(4-5-13(9)18)24(21,22)15-8-11-3-6-14(19)10(2)16(11)23-17(15)20/h3-8,19H,1-2H3
PubChem CID	20864499
ChEMBL	CHEMBL1532646
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
477425	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
117867	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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