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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL543568
Molecular formula	C13H16N2O5
IUPAC name	(2R,4R)-4-amino-1-[(4-hydroxyphenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Molecular weight	280.28
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	-4.9
Synonyms	(2R)-1-(4-Hydroxybenzyl)-4-aminopyrrolidine-2beta,4alpha-dicarboxylic acid BDBM50102114 (2R,4R)-4-amino-1-(4-hydroxybenzyl)pyrrolidine-2,4-dicarboxylic acid dihydrochloride CHEMBL1192345
Inchi Key	HILSLIXNOLWXBU-ZWNOBZJWSA-N
Inchi ID	InChI=1S/C13H16N2O5/c14-13(12(19)20)5-10(11(17)18)15(7-13)6-8-1-3-9(16)4-2-8/h1-4,10,16H,5-7,14H2,(H,17,18)(H,19,20)/t10-,13-/m1/s1
PubChem CID	44300605
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50102114
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
460255	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
115840	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
560881	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871

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