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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL52912
Molecular formula	C16H20N4
IUPAC name	2-[5-(imidazol-1-ylmethyl)-1H-indol-3-yl]-N,N-dimethylethanamine
Molecular weight	268.364
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	1.7
Synonyms	SCHEMBL6943873 BDBM50407357 N,N-Dimethyl-5-(1H-imidazol-1-ylmethyl)-1H-indole-3-(ethanamine)
Inchi Key	GXDRKMVYBOOCOD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H20N4/c1-19(2)7-5-14-10-18-16-4-3-13(9-15(14)16)11-20-8-6-17-12-20/h3-4,6,8-10,12,18H,5,7,11H2,1-2H3
PubChem CID	10400849
ChEMBL	CHEMBL52912
IUPHAR	N/A
BindingDB	50407357
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
107543	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
107542	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
107544	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
107541	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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