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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL372807
Molecular formula	C25H27ClFN3O3
IUPAC name	N-[5-chloro-2-[(E)-3-[3-[(4-fluorophenyl)methyl]-3,8-diazabicyclo[3.2.1]octan-8-yl]-3-oxoprop-1-enyl]-4-methoxyphenyl]acetamide
Molecular weight	471.957
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.6
Synonyms	SCHEMBL5240946 BDBM50174709 N-(2-(3-(3-(4-fluorobenzyl)-3,8-diaza-bicyclo[3.2.1]octan-8-yl)-3-oxoprop-1-enyl)-5-chloro-4-methoxyphenyl)acetamide
Inchi Key	GRXAAIBPDTYJKW-BJMVGYQFSA-N
Inchi ID	InChI=1S/C25H27ClFN3O3/c1-16(31)28-23-12-22(26)24(33-2)11-18(23)5-10-25(32)30-20-8-9-21(30)15-29(14-20)13-17-3-6-19(27)7-4-17/h3-7,10-12,20-21H,8-9,13-15H2,1-2H3,(H,28,31)/b10-5+
PubChem CID	44405176
ChEMBL	CHEMBL372807
IUPHAR	N/A
BindingDB	50174709
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
103857	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
103858	C-C chemokine receptor type 1	P51675	Ccr1	Mus musculus (Mouse)	355

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