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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL316187
Molecular formula	C27H23ClN2O6
IUPAC name	4-[(6-chloro-1,3-benzodioxol-5-yl)methyl]-2-[(3,5-dimethoxyphenyl)methyl]-5-phenylpyrazole-3-carboxylic acid
Molecular weight	506.939
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.7
Synonyms	1-(3,5-Dimethoxybenzyl)-3-phenyl-4-(6-chloro-1,3-benzodioxole-5-ylmethyl)-1H-pyrazole-5-carboxylic acid BDBM50094001 4-(6-Chloro-benzo[1,3]dioxol-5-ylmethyl)-2-(3,5-dimethoxy-benzyl)-5-phenyl-2H-pyrazole-3-carboxylic acid
Inchi Key	GJUNCAUBMKTRRC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H23ClN2O6/c1-33-19-8-16(9-20(12-19)34-2)14-30-26(27(31)32)21(25(29-30)17-6-4-3-5-7-17)10-18-11-23-24(13-22(18)28)36-15-35-23/h3-9,11-13H,10,14-15H2,1-2H3,(H,31,32)
PubChem CID	44320375
ChEMBL	CHEMBL316187
IUPHAR	N/A
BindingDB	50094001
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
98296	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
98297	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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