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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000712878
Molecular formula	C19H18N2O5
IUPAC name	5-[(2Z)-2-(2-ethyl-2-methyl-6-phenyl-1,3-dioxin-4-ylidene)ethylidene]-1,3-diazinane-2,4,6-trione
Molecular weight	354.362
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	2.9
Synonyms	SR-01000326074-1 BDBM59497 cid_5760788 5-[(2Z)-2-(2-ethyl-2-methyl-6-phenyl-1,3-dioxin-4-ylidene)ethylidene]-1,3-diazinane-2,4,6-trione SMR000282645 AKOS000673858 HMS2697P10 5-[(2Z)-2-(2-ethyl-2-methyl-6-phenyl-1,3-dioxin-4-ylidene)ethylidene]barbituric acid SR-01000326074 BAS 00874223 CHEMBL1540557 AC1NXW9S [ Show all ]
Inchi Key	GAGYVANRLKJATI-LCYFTJDESA-N
Inchi ID	InChI=1S/C19H18N2O5/c1-3-19(2)25-13(11-15(26-19)12-7-5-4-6-8-12)9-10-14-16(22)20-18(24)21-17(14)23/h4-11H,3H2,1-2H3,(H2,20,21,22,23,24)/b13-9-
PubChem CID	5760788
ChEMBL	CHEMBL1540557
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
474197	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
91619	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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