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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-tert-butyl-3-methyl-4-[(2-nitrophenyl)thio]-1H-pyrazol-5-yl acetate
Molecular formula	C16H19N3O4S
IUPAC name	[2-tert-butyl-5-methyl-4-(2-nitrophenyl)sulfanylpyrazol-3-yl] acetate
Molecular weight	349.405
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.5
Synonyms	MolPort-003-027-556 AKOS001753926 EU-0088229 SR-01000092605-1 MCULE-2897365830 851127-35-0 SMR000308112 F0569-0568 ZINC212756 1-(tert-butyl)-3-methyl-4-((2-nitrophenyl)thio)-1H-pyrazol-5-yl acetate MLS000729835 AC1LFN7A SR-01000092605 CHEMBL1412994 HMS2721D18 [2-tert-butyl-5-methyl-4-(2-nitrophenyl)sulfanylpyrazol-3-yl] acetate [ Show all ]
Inchi Key	GAFJIGVVQLCBPY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H19N3O4S/c1-10-14(24-13-9-7-6-8-12(13)19(21)22)15(23-11(2)20)18(17-10)16(3,4)5/h6-9H,1-5H3
PubChem CID	756445
ChEMBL	CHEMBL1412994
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
91571	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
91572	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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