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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3982726
Molecular formula	C22H30O6
IUPAC name	4-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]butanoic acid
Molecular weight	390.476
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	2.3
Synonyms	5alpha,9-Epoxy-prostaglandin F1 BDBM50206020 5,9-E-16-P-PGF1 Cyclopenta(b)pyran-2-butanoic acid, octahydro-6-hydroxy-5-(3-hydroxy-4-phenoxy-1-butenyl)-, (2R-(2alpha,4abeta,5beta(1E,3R*),6alpha,7abeta))- (5alpha)-5,9-Epoxy-16-phenoxy PGF(1) 72657-07-9 5,9-Epoxy-16-phenoxy-PGF1 5alpha,9-Epoxy-PGF1 4-[(2R,4aR,5R,6R,7aS)-6-hydroxy-5-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-2,3,4,4a,5,6,7,7a-octahydrocyclopenta[b]pyran-2-yl]butanoic acid AC1O5ZSK 5,9-Epoxy-16-phenoxy-prostaglandin F1 [ Show all ]
Inchi Key	FTBNLUSUCXCIGD-OVCPVMRKSA-N
Inchi ID	InChI=1S/C22H30O6/c23-15(14-27-16-5-2-1-3-6-16)9-11-18-19-12-10-17(7-4-8-22(25)26)28-21(19)13-20(18)24/h1-3,5-6,9,11,15,17-21,23-24H,4,7-8,10,12-14H2,(H,25,26)/b11-9+/t15-,17-,18-,19-,20-,21+/m1/s1
PubChem CID	6443852
ChEMBL	CHEMBL3982726
IUPHAR	N/A
BindingDB	50206020
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
538147	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
538145	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
538146	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359

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