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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL127194
Molecular formula	C23H25ClN2O3S
IUPAC name	(E)-3-[2-butyl-3-[(2-chlorophenyl)methyl]imidazol-4-yl]-2-[(5-methoxythiophen-2-yl)methyl]prop-2-enoic acid
Molecular weight	444.974
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.9
Synonyms	3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-(5-methoxy-thiophen-2-ylmethyl)-acrylic acid SCHEMBL684121 (E)-3-[2-Butyl-3-(2-chlorobenzyl)-3H-imidazol-4-yl]-2-[(5-methoxy-2-thienyl)methyl]propenoic acid SCHEMBL6960120 BDBM50003292 L004554 [ Show all ]
Inchi Key	FKESYUCPUPIGSS-SFQUDFHCSA-N
Inchi ID	InChI=1S/C23H25ClN2O3S/c1-3-4-9-21-25-14-18(26(21)15-16-7-5-6-8-20(16)24)12-17(23(27)28)13-19-10-11-22(29-2)30-19/h5-8,10-12,14H,3-4,9,13,15H2,1-2H3,(H,27,28)/b17-12+
PubChem CID	9933179
ChEMBL	CHEMBL127194
IUPHAR	N/A
BindingDB	50003292
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
80347	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359

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