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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1B angiotensin II receptor
Species	Rattus norvegicus (Rat)
Gene	Agtr1b
Synonym	Angiotensin II type-1B receptor AT1B AT3
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKNTPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPSDNMSSSAKKSASFFEVE
UniProt	P29089
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL263
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL127194
Molecular formula	C23H25ClN2O3S
IUPAC name	(E)-3-[2-butyl-3-[(2-chlorophenyl)methyl]imidazol-4-yl]-2-[(5-methoxythiophen-2-yl)methyl]prop-2-enoic acid
Molecular weight	444.974
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50003292 L004554 3-[2-Butyl-3-(2-chloro-benzyl)-3H-imidazol-4-yl]-2-(5-methoxy-thiophen-2-ylmethyl)-acrylic acid SCHEMBL684121 (E)-3-[2-Butyl-3-(2-chlorobenzyl)-3H-imidazol-4-yl]-2-[(5-methoxy-2-thienyl)methyl]propenoic acid SCHEMBL6960120 [ Show all ]
Inchi Key	FKESYUCPUPIGSS-SFQUDFHCSA-N
Inchi ID	InChI=1S/C23H25ClN2O3S/c1-3-4-9-21-25-14-18(26(21)15-16-7-5-6-8-20(16)24)12-17(23(27)28)13-19-10-11-22(29-2)30-19/h5-8,10-12,14H,3-4,9,13,15H2,1-2H3,(H,27,28)/b17-12+
PubChem CID	9933179
ChEMBL	CHEMBL127194
IUPHAR	N/A
BindingDB	50003292
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	90.0 nM	PMID1433195	BindingDB,ChEMBL

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