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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001116411
Molecular formula	C22H27ClFN3O2S
IUPAC name	4-chloro-N-[2-[4-(2-fluorophenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide
Molecular weight	451.985
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.6
Synonyms	4-chloro-N-[2-[4-(2-fluorophenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide CHEMBL1711436 AKOS001512863 MCULE-6306605577 4-chloranyl-N-[2-[4-(2-fluorophenyl)piperazin-1-yl]cyclohexyl]benzenesulfonamide CCG-143160 MolPort-007-686-590 4-chloro-N-[2-[4-(2-fluorophenyl)piperazino]cyclohexyl]benzenesulfonamide cid_23604969 AKOS022045384 4-chloro-N-[2-[4-(2-fluorophenyl)-1-piperazinyl]cyclohexyl]benzenesulfonamide SMR000625526 4-chloro-N-{2-[4-(2-fluorophenyl)piperazin-1-yl]cyclohexyl}benzenesulfonamide HMS2929O16 BDBM91037 MLS003880607 [ Show all ]
Inchi Key	FFNDTDNFSMPSTD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27ClFN3O2S/c23-17-9-11-18(12-10-17)30(28,29)25-20-6-2-4-8-22(20)27-15-13-26(14-16-27)21-7-3-1-5-19(21)24/h1,3,5,7,9-12,20,22,25H,2,4,6,8,13-16H2
PubChem CID	23604969
ChEMBL	CHEMBL1711436
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
77239	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
77238	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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