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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL487508
Molecular formula	C20H25Cl2NO3
IUPAC name	(2S)-1-(2,3-dichlorophenoxy)-3-[[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino]propan-2-ol
Molecular weight	398.324
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.6
Synonyms	SCHEMBL14383121 (2S)-1-[(2,3-Dichlorophenyl)oxy]-3-((1,1-dimethyl-2-[4-(methyloxy)phenyl]ethyl)amino)-2-propanol BDBM50268076
Inchi Key	DWAKJSOEJNKPME-HNNXBMFYSA-N
Inchi ID	InChI=1S/C20H25Cl2NO3/c1-20(2,11-14-7-9-16(25-3)10-8-14)23-12-15(24)13-26-18-6-4-5-17(21)19(18)22/h4-10,15,23-24H,11-13H2,1-3H3/t15-/m0/s1
PubChem CID	44186438
ChEMBL	CHEMBL487508
IUPHAR	N/A
BindingDB	50268076
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
70424	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
70422	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
70423	Extracellular calcium-sensing receptor	P41180	CASR	Homo sapiens (Human)	1078

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