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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL102040
Molecular formula	C30H36N2O2
IUPAC name	N-methyl-2,3-diphenyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]cycloprop-2-ene-1-carboxamide
Molecular weight	456.63
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.3
Synonyms	2,3-Diphenyl-N-methyl-N-[(5R,7S,8S)-7-pyrrolizino-1-oxaspiro[4.5]decane-8-yl]-2-cyclopropene-1-carboxamide
Inchi Key	DVBJTNONUUBBIZ-QRQMUESOSA-N
Inchi ID	InChI=1S/C30H36N2O2/c1-31(24-15-17-30(16-10-20-34-30)21-25(24)32-18-8-9-19-32)29(33)28-26(22-11-4-2-5-12-22)27(28)23-13-6-3-7-14-23/h2-7,11-14,24-25,28H,8-10,15-21H2,1H3/t24-,25-,30-/m0/s1
PubChem CID	11753832
ChEMBL	CHEMBL102040
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
69767	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
69768	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
69766	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398

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