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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL515034
Molecular formula	C21H21F3N4O
IUPAC name	1-methyl-2-[[(1R,5S)-6-[[5-(trifluoromethyl)pyridin-2-yl]oxymethyl]-3-azabicyclo[3.1.0]hexan-3-yl]methyl]benzimidazole
Molecular weight	402.421
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.4
Synonyms	BDBM50263433 1-methyl-2-(((1R,5S)-6-((5-(trifluoromethyl)pyridin-2-yloxy)methyl)-3-aza-bicyclo[3.1.0]hexan-3-yl)methyl)-1H-benzo[d]imidazole
Inchi Key	DTMCLRWXKBKQIR-XYPWUTKMSA-N
Inchi ID	InChI=1S/C21H21F3N4O/c1-27-18-5-3-2-4-17(18)26-19(27)11-28-9-14-15(10-28)16(14)12-29-20-7-6-13(8-25-20)21(22,23)24/h2-8,14-16H,9-12H2,1H3/t14-,15+,16?
PubChem CID	25110723
ChEMBL	CHEMBL515034
IUPHAR	N/A
BindingDB	50263433
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
68440	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559446	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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